Iowa State vs. Kansas State 2025 NCAAF Odds, Time, and Prediction

They call it “Farmageddon,” but this year’s edition comes with a twist. It’s not played in a Midwest farmland but on neutral turf in Dublin, Ireland. Historically, Iowa State holds a slim edge in the rivalry (54–50–4), and they’ve owned the recent stretch, winning 4 of the last 5, including back-to-back wins with coach Matt Campbell at the helm.

Kansas State enters 2025 as a co-favorite for the Big 12 title and a slight betting favorite in this opener (-3 spread). But they’ll have their hands full. Iowa State is riding high after the best season in program history and won’t be backing down.

Iowa State vs. Kansas State Week 0 Odds

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When, Where, and How to Watch?

• Place: Aviva Stadium in Dublin, Ireland
• Date: Saturday, August 23, 2025
• Time: 11:00 a.m. ET
• How to Watch: ESPN

Can Iowa State Upset the NCAAF Odds?

Iowa State is coming off the best year in program history, a stellar 11–3 run that ended with a Big 12 title game appearance. They’re bringing back 12 starters in 2025, including star quarterback Rocco Becht, who’s quickly become the face of the offense.

On defense, they’re stacked with elite players like Jeremiah Cooper in the secondary and Domonique Orange clogging the trenches. Add to that the steady hand of Matt Campbell, now in his 10th year running the show, and you’ve got a team with serious potential.

They also have a relatively good record against Kansas State, who are among their top rivals. Last season, they beat the Wildcats 29:21, punching their ticket to the conference championship.

Can they do it again? Betting odds see them as slight underdogs, but they’re taking the Week 0 game super seriously. The thing is that in a conference as deep as the Big 12, there’s no room for slip-ups. A stumble in Dublin could derail their title dreams before the plane even lands back in Ames.

Reasons Why Oddsmakers Favor Kansas State in 2025 Week 0

Kansas State enters Week 0 with stability at the top, with coach Chris Klieman kicking off his seventh season on August 23. This guy is famous for instilling consistency and discipline in the team, so don’t expect to see any big slips happening to the Wildcats in 2025.

Last season, they went 9-4, and they will probably be somewhere around those numbers in 2025. Sure, their fans have all the reasons to hope for an even better record, given that their key men have grown and gained valuable experience.

This goes especially for QB Avery Johnson, who’s coming off a breakout campaign that saw him racking up 2,700 passing yards and 600 on the ground. He flashed real dual-threat potential, and this could be the year when he turns into a real NCAAF star.

K‑State didn’t stand still in the offseason, either. They added RB Dylan Edwards to bolster the backfield and made upgrades to their wide receiver corps, aiming to sharpen Johnson’s efficiency, particularly his 58% completion rate.

Iowa State vs. Kansas State Prediction

Aer Lingus Classic games are famously very thrilling, with four of the last five being decided by less than a touchdown. It’s a similar case with Iowa State vs. Kansas State duels, which often are decided by a field goal. We think that might be the case with their Week 0 game on August 23.

That’s why we’re backing the underdog – Iowa State. We think they’re going to give K-State real war. We’re not 100% certain that they’re going to win, but we think they won’t lose by more than 3 points.

Pick: Iowa State +3